Conference Papers & Presentations

PEER-REVIEW CONFERENCE PUBLICATIONS

Ajitha Kommalapati, Laliotis G, Jordan Rich, Shivaram Cumarasamy, Samuel Rivero-Hinojosa, Shruti Sharma, Charuta C Palsuledesai, Meenakshi Malhotra, Matt D. Galsky, Adam ElNaggar, Minetta C. Liu, John P. Sfakianos, Charles Peyton, James Ferguson, Arnab Basu. Performance of a tumor-informed molecular residual disease (MRD) assay in resected bladder cancer with mixed or pure variant histology: Analysis of a real-world multicenter cohort. J Clin Oncol 42, 649-649(2024) [abstract]

Reuben Ben-David, Alex Chehrazi-Raffle, Laliotis G, Neeraja Tillu, Shivaram Cumarasamy, Jordan Rich, Kevin Manage, Shruti Sharma, Punashi Dutta, Meenakshi Malhotra, Adam ElNaggar, Minetta C. Liu, Adam Rock, Tanya B. Dorff, John P. Sfakianos. Longitudinal tumor-informed ctDNA assay and patient outcomes in testicular cancer. J Clin Oncol 42, 499-499(2024) [abstract]

Rebecca Hassoun, Clint Cary, Timothy A. Masterson, Laliotis G, Shruti Sharma, Punashi Dutta, Meenakshi Malhotra, Adam ElNaggar, Minetta C. Liu, John P. Sfakianos, Jennifer King, Lawrence H. Einhorn, Nabil Adra. Utility of circulating tumor DNA (ctDNA) as a predictive biomarker for disease monitoring in patients with non-seminomatous germ-cell tumor (NSGCT). J Clin Oncol 42, 500-500(2024) [abstract]

Michael Cecchini, Ronald R. Salem, Marie Robert, Suzanne Czerniak, Ondrej Blaha, Daniel Zelterman, Moein Rajaei, Jeffrey P. Townsend, Guoping Cai, Sumedha Chowdhury, Deanne Yugawa, Robert Tseng, Carlos Mejia Arbelaez, Jingjing Jiao, Luisa Escobar-Hoyos, Kenneth Shroyer, Jaykumar Thumar, Jeremy Kortmansky, Wajih Zaheer, Neal Fischbach, Justin Persico, Stacey Stein, Sajid A. Khan, Charles Cha, Kevin G. Billingsley, John W. Kunstman, Kimberly L. Johung, Christina Wiess, Mandar D. Muzumdar, Erik Spickard, Vasily N. Aushev, Laliotis G, Adham Jurdi, Minetta C. Liu, Jill Lacy. A phase II study of peri-operative modified FOLFIRINOX in localized pancreatic ductal adenocarcinoma (PDAC). Cancer Res (2024) 84 (2_Supplement): A002 [abstract]

Hiroki Yukami, Yoshiaki Nakamura, Saori Mishima, Koji Ando, Hideaki Bando, Jun Watanabe, Keiji Hirata, Naoya Akazawa, Masataka Ikeda, Mitsuru Yokota, Kentaro Kato, Laliotis G, Vasily N. Aushev, Adham A Jurdi, Minetta Liu, Daisuke Kotani, Eiji Oki, Ichiro Takemasa, Takeshi Kato, Takayuki Yoshino. Circulating tumor DNA (ctDNA) dynamics in patients with colorectal cancer (CRC) with molecular residual disease: Updated analysis from GALAXY study in the CIRCULATE-JAPAN. J Clin Oncol 42, 6-6(2024) [abstract]

Saori Mishima, Daisuke Kotani, Yoshiaki Nakamura, Hideaki Bando, Masaaki Miyo, Atsushi Hamabe, Jun Watanabe, Keiji Hirata, Naoya Akazawa, Kozo Kataoka, Kun-Huei Yeh, Laliotis G, Adham Jurdi, Minetta Liu, Hiroya Taniguchi, Ichiro Takemasa, Takeshi Kato, Takayuki Yoshino, Eiji Oki. Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: GALAXY study in the CIRCULATE-Japan. Annals of Oncology, 34(S415-S416), 2023 Nov; doi : https://doi.org/10.1016/j.annonc.2023.09.123 [abstract]

Chiara Molinari, Giorgia Marisi, Laliotis G, Erik Spickard, Ilario Giovanni Rapposelli, Elisabetta Petracci, Giby V. George, Shruti Sharma, Adham Jurdi, Himanshu Sethi, Minetta C. Liu, Paola Ulivi, Matteo Canale, Luca Saragoni, Riccardo Panzacchi, Giovanni Luca Frassineti, Margherita Muratore, Antonino Romeo, Giovanni Martinelli, Alessandro Passardi. Assessment of circulating tumor (ct)DNA in patients (pts) with locally advanced rectal cancer (LARC) treated with neoadjuvant therapy (NAT). Annals of Oncology, 34(S438), 2023 Oct [abstract]

Yoshiaki Nakamura, Daisuke Kotani, Saori Mishima, Hiroki Yukami, Jun Watanabe, Naoya Akazawa, Kozo Kataoka, Keiji Hirata, Kentaro Yamazaki, Kun-Huei Yeh, Laliotis G, Vasily N. Aushev, Adham Jurdi, Masahito Kotaka, Hideaki Bando, Hiroya Taniguchi, Ichiro Takemasa, Takeshi Kato, Takayuki Yoshino, Eiji Oki. Circulating tumor (ct)DNA as a prognostic biomarker in patients (pts) with resected colorectal cancer (CRC): an updated 24 months (mos) disease free survival (DFS) analysis from GALAXY study (CIRCULATE-Japan). Annals of Oncology, 34(S415-S416), 2023 Oct [abstract]

Jun Watanabe, Eiji Oki, Daisuke Kotani, Yoshiaki Nakamura, Saori Mishima, Hideaki Bando, Hiroki Yukami, Koji Ando, Masaaki Miyo, Keiji Hirata, Naoya Akazawa, Kun-Huei Yeh, Laliotis G, Adham A Jurdi, Minetta Liu, Hiroya Taniguchi, Ichiro Takemasa, Takeshi Kato, Masaki Mori, Takayuki Yoshino. Postoperative circulating tumor DNA-based molecular residual disease in patients with BRAF V600E and MSI-H colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan. JCO Global Oncology 9, 2023 (suppl 1; abstr 32).[abstract]

Ajitha Kommalapati, Laliotis G, Michael Glover, Grayce Selig,, Tamara Mahmood, Sumit Shah, Christopher J. Hoimes, Tyler F. Stewart, Shruti Sharma, Meenakshi Malhotra, Natalia Pajak, Mark Calhoun, Adam ElNaggar, Minetta C. Liu, Arnab Basu, Alan Tan, Matt D. Galsky. Association of Tumor- Informed Minimal Residual Disease (MRD) with Clinical Outcomes for Muscle Invasive Bladder Cancer (MIBC) – A Multicenter Retrospective Real World Analysis. J Clin Oncol 41, 2023 (suppl 16; abstr 3050) [abstract]

Changhoon Yoo, Laliotis G, Hyehyun Jeong, Jae Ho Jeong, Kyu-Pyo Kim, Seonmin Lee, Baek-Yeol Ryoo, Shruti Sharma, Punashi Dutta, Meenakshi Malhotra, Adham Jurdi, Minetta Liu. Utility of circulating tumor DNA (ctDNA) as a predictive biomarker for disease monitoring in patients (pts) with cholangiocarcinoma (CCA) before and during adjuvant chemotherapy (ACT): sub-analysis of the randomized phase 2 STAMP trial. J Clin Oncol 41, 2023 (suppl 16; abstr 4123) [abstract]

Eiji Oki, Daisuke Kotani, Yoshiaki Nakamura, Saori Mishima, Hideaki Bando, Hiroki Yukami, Koji Ando, Masaaki Miyo, Jun Watanabe, Keiji Hirata, Naoya Akazawa, Kun-Huei Yeh, Laliotis G, Shruti Sharma, Minetta Liu, Hiroya Taniguchi, Ichiro Takemasa, Takeshi Kato, Masaki Mori, Takayuki Yoshino. Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan. J Clin Oncol 41, 2023 (suppl 16; abstr 3521) [abstract]

Marco Gerlinger, Anderley Gordon, Louise J Barber, Laliotis G, Avani Athauda, Benjamin Challoner, Andrew Woolston, Sonia Mansukhani, Matt Dunstan, Nikoletta Petrou, Komel Khabra, Retchel Lazaro-Alcausi, Richard Crux, Victoria Borja, Ruwaida Begum, Isma Rana, Charuta Palsuledesai, Meenakshi Malhotra, Minetta Liu, Adham Jurdi, Shruti Sharma, Sheela Rao, Sacheen Kumar, David Cunningham, Ian Chau, Naureen Starling, M Asif Chaudry. Circulating tumor DNA for recurrence prediction and efficacy analysis in the ICONIC trial of peri-operative FLOT and avelumab (PD-L1) in localized esophago-gastric adenocarcinoma. Cancer Research 83, no. 7_Supplement (2023): 5591-5591. [abstract]

Sia Viborg Lindskrog, Laliotis G, Karin Birkenkamp-Demtröder, Iver Nordentoft, Philippe Lamy, Elshaddai Z White, Natalia Pajak, Tine G Andreasen, Punashi Dutta, Meenakshi Malhotra, Shruti Sharma, Mark Calhoun, Adam ElNaggar, Minetta C Liu, Mads Agerbæk, Jørgen B Jensen, Lars Dyrskjøt. Utility of circulating tumor DNA and transcriptomic profiling in predicting outcome in muscle invasive bladder cancer patients. Cancer Research 83, no. 7_Supplement (2023): 5600-5600. [abstract]

Shivaram Cumarasamy, Laliotis G, Elshaddai White, Jordan Rich, Punashi Dutta, Shruti Sharma, Mark Calhoun, Adam Elnaggar, Minetta Liu, Kyrollis Attalla, Reza Mehrazin, Peter Wiklund, John Sfakianos. Assessment of circulating tumor DNA status as a prognostic marker for recurrence detection in patients with muscle invasive bladder cancer. The Journal of Urology 209, no. Supplement 4 (2023): e981. [abstract]

Lars Dyrskjøt, Laliotis GI, Iver Nordentoft, Karin Birkenkamp-Demtröder, Sia Viborg Lindskrog, Philippe Lamy, Elshaddai White, Natalia Pajak, Tine Ginnerup Andreasen, Punashi Dutta, Shruti Sharma, Mark Calhoun, Adam ElNaggar, Minetta C. Liu, Mads Agerbaek, and Jørgen Bjerggaard Jensen. Utility of ctDNA in predicting outcome and pathological complete response in bladder cancer patients as a guide for selective bladder preservation strategies. Journal of Clinical Oncology 41, no. 6_suppl (February 20, 2023) 563-563 [abstract]

Stacey A. Cohen, Pashtoon M. Kasi, Vasily N. Aushev, Diana L. Hanna, Gregory P. Botta, Saima Sharif, Laliotis GI, Vivek Sharma, Ali Alqahtani, Sreenivasa R. Chandana, Sandra Kang, Sakti Chakrabarti, Bradley G. Somer, Anup Kasi, Farshid Dayyani, Midhun Malla, Adham Jurdi, Minetta C. Liu, Alexey Aleshin, Scott Kopetz. Kinetics of postoperative circulating cell-free DNA and impact on minimal residual disease detection rates in patients with resected stage I-III colorectal cancer. J Clin Oncol 41, 2023 (suppl 4; abstr 5) [abstract]

Enrique Sanz-Garcia, Laliotis G, Lisa Avery, Anna Spreafico, Aaron R Hansen, Lawson Eng.abstract, Nitthusha Singaravelan, Stephen Willingham, Shirin Soleimani, Trevor Pugh, Scott Bratman, Lillian L Siu. Early circulating tumor DNA kinetics and gene expression profiling to predict treatment outcomes with anti-PD-1 therapy. IOTECH, 16 (S1), 2022 Dec 01 [abstract]

Laliotis G, Lin, P.H.  Pancancer genomic analysis reveals histone H3K36 and H3K27 modifiers and readers as prognostic factors in patients with cancer. Cancer Res (2022) 82 (23_Supplement_2): B032 [abstract]

Laliotis G, Lin, P.H.  Deciphering the transcriptomic landscape of AKT isoforms and its prognostic impact in patients with lung adenocarcinoma. Cancer Res (2022) 82 (23_Supplement_2): A031 [abstract]

Laliotis G, Lin, P.H.  Deciphering the micro-RNA landscape of AKT isoforms and its clinical impact in patients with lung adenocarcinoma. Cancer Res (2022) 82 (23_Supplement_2): A030 [abstract]

SA Cohen, PM Kasi, VN Aushev, DL Hanna, GP Botta, S Sharif, Laliotis G, S Sharma, V Sharma, A Alqahtani, SR Chandana, S Kang, S Chakrabarti, BG Somer, A Kasi, F Dayyani, M Malla, A Jurdi, A Aleshin, S Kopetz. Real-world monitoring of circulating tumor DNA reliably predicts cancer recurrence in patients with resected stages I-III colorectal cancer. Annals of Oncology, 33(S683-S684), 2022 Sept 01 [abstract]

Issa, M., Husain M., Klamer B., Laliotis G, Mladkova N., Karivedu V., Bhateja P, Dibs K., Pan J., Grecula, J.C. and Jhawar, S.R., M Old, DL Mitchell, S Baliga, R Carrau, JW Rocco, DM Blakaj, M Bonomi 2022. Impact of Tobacco, Marijuana and Alcohol Use on Overall Survival in Recurrent Metastatic Head and Neck Cancer Patients Treated with Immune Checkpoint Inhibitors. International Journal of Radiation Oncology, Biology, Physics, 112(5), p.e38 [abstract]

K. Dibs, N. Mladkova, D.J. DiCostanzo, S. Baliga, M.E. Gamez, S.R. Jhawar, D.L. Mitchell, A. Ewing, M. Issa, V. Karivedu, J.D. Palmer, P. Bhateja, Laliotis GI, D.J. Konieczkowski, J.C. Grecula, M. Old, J.W. Rocco, M. Bonomi, D.M. Blakaj, Brachial Plexus Tolerance to High-Dose Radiation in the Re-Irradiation Setting. International Journal of Radiation Oncology, Biology, Physics. 2021 Nov 1;111(3):e240-1 [abstract]

M. Issa, B. Klamer, P. Bhateja, V. Karivedu, Laliotis GI, K. Dibs, N. Mladkova, X. Pan, M. Old, M. Gamez, J. Grecula, S. Jhawar, D. Mitchell, S. Baliga5, R. Carrau, J. Rocco, M. Bonomi, D. Blakaj. Clinical predictors for survival with the addition of chemotherapy in patients with recurrent-metastatic squamous cell carcinoma of the head and neck after progression on immune checkpoint inhibitors. Annals of Oncology, 32(S797-S798), 2021 Sept 01 [abstract]

Anuvrat Sircar, Satishkumar Singh, Laliotis GI, Evangelia Chavdoula, Amber Hart, Philip N. Tsichlis, Lalit Sehgal. Role of the FGFR1-KDM2B-EZH2 signaling axis in bone-marrow microenvironment mediated tumor survival & drug resistance in Mantle cell lymphoma, Cancer Res July 1 2021 (81) (13 Supplement) 1114 [abstract]

Laliotis GI, Issa M, Klamer B, Karivedu V, Bhateja P, Dibs K, Pan X, Old M, Gamez M, Grecula J, Jhawar S, Mitchell D, Baliga S, Carrau R, Rocco J, Blakaj D, Bonomi M. Expansion cohort validation of a clinical predictive model for head and neck cancer survival in patients treated with immune checkpoint inhibitors. J Clinical Oncology 2021 May 20; 39, no. 15_suppl 6030-6030 [abstract]

Majd Issa, Brett Klamer, Vidhya Karivedu, Priyanka Bhateja, Laliotis GI, Khaled Dibs, Nikol Mladkova, Xueliang Jeff Pan, Matthew O. Old, Mauricio Gamez, John C. Grecula, Sachin R Jhawar, Darrion L Mitchell, Sujith Baliga, Ricardo Carrau, James William Rocco, Dukagjin Blakaj, and Marcelo Raul Bonomi. Use of cetuximab added to weekly chemotherapy to improve progression-free survival in patients with recurrent metastatic head and neck squamous cell carcinoma after progression on immune checkpoint inhibitors. Journal of Clinical Oncology 2021 May 20;39:15_suppl, 6038-6038 [abstract]

Laliotis GI, Evangelia Chavdoula, Abdul Kaba, Alessandro La Ferlita, Vollter Anastas, Arturo Orlacchio, Lalit Sehgal, David P. Carbone, Vincenzo Coppola and Philip N. Tsichlis. The inhibition of IWS1 phosphorylation promotes genomic instability, the cGAS/STING pathway activation and PD-L1 levels, through the U2AF2 alternative RNA splicing and Sororin expression. Cancer Immunol Res February 1 2021 (9) (2 Supplement) PO010 [abstract]

Laliotis GI, Adam D. Kenney, Evangelia Chavdoula, Arturo Orlacchio, Vollter Anastas, Alessandro La Ferlita, Abdul Kaba, Lalit Sehgal, Vincenzo Coppola, Jacob S. Yount and Philip N. Tsichlis. Sensitivity of cancer cells to oncolytic viruses is defined by IWS1 phosphorylation dependent epigenetic regulation of U2AF2 splicing and nucleocytoplasmic export of type I IFN transcripts, Cancer Immunol Res February 1 2021 (9) (2 Supplement) PO088 [abstract]

Laliotis GI, Evangelia Chavdoula, Maria D. Paraskevopoulou, Abdul Kaba, Alessandro La Ferlita, VollterAnastas, Arturo Orlacchio, Vasiliki Taraslia, Ioannis Vlachos, Marina Capece, Artemis Hatzigeorgiou, Dario Palmieri, Salvatore Alaimo, Christos Tsatsanis, Lalit Sehgal, David P. Carbone, Vincenzo Coppola, Philip N. Tsichlis. IWS1 phosphorylation promotes tumor growth and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the epigenetic regulation of U2AF2 RNA splicing. Cancer Res December 02 2020;80(23 Suppl) PO-011 [abstract]

Laliotis GI, Evangelia Chavdoula, Maria D. Paraskevopoulou, Vollter Anastas, Ioannis Vlachos, Vasiliki Tarasslia, Artemis Hatzigeorgiou, Dario Palmieri, Abdul Kaba, Marina Capece, Arturo Orlacchio, Lalit Sehgal, Vincenzo Coppola and Philip N. Tsichlis. Alternative RNA splicing of U2AF2, induced by AKT3-phosphorylated IWS1, promotes tumor growth, by activating a CDCA5-ERK positive feedback loop. Cancer Res August 15 2020 (80) (16 Supplement) 3649 [abstract]

Laliotis GI, Adam D. Kenney, Arturo Orlacchio, Vincenzo Coppola, Jacob S. Yount and Philip N. Tsichlis. Sensitivity of cancer cells to oncolytic viruses is defined by IWS1 phosphorylation dependent epigenetic regulation of U2AF2 splicing and nucleocytoplasmic export of type I IFN transcripts., Cancer Res August 15 2020 (80) (16 Supplement) LB-183; doi:10.1158/1538-7445.AM2020-LB-183 [abstract]

Shouvonik Sengupta, Lindsay M Webb, Laliotis GI, Philip N Tsichlis and Mireia Guerau-de-Arellano. Role of PRMT5 in cholesterol metabolism and Th17 pathogenicity. J Immunol May 1, 2020,  204 (1 Supplement) 76.7 [abstract]

Zayda L Piedra-Quintero, Shouvonik Sengupta, Lindsay M Webb, Stephanie A Amici, Laliotis GI, Philip N Tsichlis, Mireia Guerau-de-Arellano. PRMT5 controls pathogenicity and metabolic genes during Th17 polarization. J Immunol May 1, 2020,  204 (1 Supplement) 230.1 [abstract]